Postdoctoral Research Scholar in Bioinformatics and Computational Biology

Arizona State University

Arizona State University

Tempe, AZ, USA
Posted on Sep 16, 2025

Arizona State University: Knowledge Enterprise: Biodesign Institute: Biodesign Center for Biocomputing, Security and Society

Location

Tempe Campus

Open Date

Sep 12, 2025

Description

The Arizona Cancer Evolution (ACE) Center at Arizona State University is recruiting a postdoctoral fellow in bioinformatics/computational biology/systems biology. Ideal candidates would have expertise in developing packages to analyze genomic DNA, RNA, methylation, and immune receptor (TCR/BCR) data, particularly from cancer samples, as well as expertise in evolution. Research experiences in machine/deep learning is a plus. The postdoc will have access to all of the ACE data, the Human Tumor Atlas Network data, and new data from the ~1,000 participants in the ARPH-H ADAPT clinical trial. The postdoc will be co-mentored by Drs. Carlo Maley and Heewook Lee, and will be supported in developing their own independent research program. Funding is available for 3 years with the potential for renewal.

Essential Duties

  • Analysis of genomic data (DNA, RNA and methylation) from cancers and other tissues.
  • Setting up bioinformatics pipelines to measure evolutionary and ecological parameters of tumor samples
  • Developing algorithms and pipelines to calculate HLA type and measures of T-cell receptor repertoire
  • Running those pipelines on -omic data (DNA, RNA and methylation) generated from tumor samples.
  • Analysis of the resulting measures from the clinical samples
  • Preparation of progress reports and scientific manuscripts
  • Presentation of scientific results

Qualifications

Minimum Qualifications

  • Applicants must have a recent Ph.D. (within the past five years) in Bioinformatics, Computational Biology, Systems Biology or related fields.

Desired Qualifications

  • Experience with developing bioninformatics software to analyze DNA, RNA and methylation data, as well as T-cell receptors and HLA typing.
  • Expertise in bioinformatics, biostatistics or computational biology, particularly in genomic analysis of cancers, as well as evolutionary analyses.
  • Expertise in machine/deep learning would be a plus.

Application Instructions

Only electronic submissions will be reviewed. Incomplete applications will not be considered. To apply for this position, submit the following required application materials:

  • Cover letter
  • A complete curriculum vitae
  • The names and contact information of three references (name, position, title, organization, email, and phone number).
  • Optional (I.e. statement of research, two or more peer-reviewed publications)

The initial application deadline is September 25, 2025. Applications will continue to be accepted on a rolling basis for a reserve pool. Applications in the reserve pool may then be reviewed in the order in which they were received until the position is filled.