RESEARCH SCIENTIST/ENGR 1
University of Washington Bothell
USD 4,276-7,765 / month
Posted on Jul 1, 2025
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| As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills, and dedication to build stronger minds and a healthier world. UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits, and natural beauty. This position may assist with several projects in the lab. In one project, we are trying to understand the molecular mechanism of action of a selfish genetic element that consists of a toxin and its antidote. In another project, we are working on mechanisms of neuromodulatory signaling and release of peptide hormones. POSITION PURPOSE The RSE1 position (also known as an entry level "Research Technician") will typically involve a combination of research activities and lab management activities. The ideal candidate may be relatively new to research with some experience, but is expected to transition into a role of more limited supervision after initial training. The position will typically will have their own independent research projects as well as supporting other projects in the lab. DUTIES AND RESPONSIBILITIES Designing and performing experiments (80%). The duties of the position will be to perform experiments deciphering the molecular mechanism of the peel-1/zeel-1 antidote of C. elegans, as well as providing support to deciphering the function of the Rab2 effector RUND-1 in dense-core vesicle biogenesis. Techniques used will include molecular biology (PCR, cloning, CRISPR/Cas9), protein expression and purification, protein activity assays, fluorescence confocal microscopy, and genetics. Specific tasks will include expressing and purifying proteins such as PEEL-1, ZEEL-1, PMPL-1, RAB-2, RUND-1, and TBC-8; performing PEEL-1 activity assays and binding to PMPL-1 and ZEEL-1; performing RAB-2 GTPase activity assays; performing structure-function analysis of PEEL-1, PMPL-1, and ZEEL-1 through mutagenesis and functional assays in C. elegans and mammlian cells; performing structure function of RUND-1 similarly. Meetings and seminars (10%) This position will involve attending a weekly lab meeting and other relevant meetings and seminars related to the field of the work. General tasks to support the lab (10%) A small portion of the time will be spent on tasks to support the overall function of the lab, including tasks such as ordering, equipment maintenance and repair. MINIMUM REQUIREMENTS Bachelor's Degree in Biochemistry or Biology and one year of relevant laboratory work, OR equivalent combination of education/experience. ADDITIONAL REQUIREMENTS Previous work in a laboratory • A practical understanding of basic methods in molecular biology • Strong organizational skills • Ability to learn new research techniques • Excellent oral and written communication skills • Ability to work as part of a team in a collaborative environment • Demonstrated ability to hold position of responsibility for extended period of time ADDITIONAL REQUIREMENTS Application Process: The application process may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are access ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed. | ||||||||||||||||||||||
| Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming. The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information. To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 or dso@uw.edu. Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law. | ||||||||||||||||||||||